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How LACRISERT® Works

LACRISERT® is a small insert that is placed into the pocket of your lower eyelid. Once inserted, LACRISERT® gently begins to dissolve within minutes.1

For most LACRISERT® users, just one insert placed in each eye in the morning lasts the entire day. But you may need to use it twice a day for symptom relief.1

LACRISERT® softens as it dissolves slowly to stabilize the tear film.1 This allows your natural tears to be preserved throughout the day.2 As your tear film thickens, it can protect the surface of your eyes longer, and you should begin to feel relief from your Dry Eye symptoms.1

LACRISERT® has been proven to relieve the following symptoms1,2:

  • Dryness
  • Soreness
  • Pain or stinging
  • Itchiness
  • Burning
  • Excessive tearing
  • Foreign body sensation
  • Sensitivity to light
  • Blurred vision
  • Redness

LACRISERT® users usually experience symptom relief within 2 weeks of beginning treatment, but there is a chance that it may take longer for your symptoms to improve.1,3,4

Most Dry Eye sufferers experience optimal improvement by 6 to 9 weeks.5 Your eye care professional will advise you on how long you should use LACRISERT®.

Indications and Usage

LACRISERT® is indicated in patients with moderate to severe Dry Eye syndromes, including keratoconjunctivitis sicca. LACRISERT® is indicated especially in patients who remain symptomatic after an adequate trial of therapy with artificial tear solutions. LACRISERT® is also indicated for patients with exposure keratitis, decreased corneal sensitivity, and recurrent corneal erosions.

Important Safety Information

LACRISERT® is contraindicated in patients who are hypersensitive to hydroxypropyl cellulose. Instructions for inserting and removing LACRISERT® should be carefully followed. If improperly placed, LACRISERT® may result in corneal abrasion. Because LACRISERT® may cause transient blurred vision, patients should be instructed to exercise caution when driving or operating machinery. Patients should be cautioned against rubbing the eye(s) containing LACRISERT®.

The following adverse reactions have been reported, but were in most instances, mild and temporary: transient blurring of vision, ocular discomfort or irritation, matting or stickiness of eyelashes, photophobia, hypersensitivity, eyelid edema, and hyperemia.

Talk to your doctor if you have side effects that bother you or that do not go away. You are encouraged to report side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch or call 1-800-FDA-1088.

References: 1. Lacrisert [prescribing information]. Lawrenceville, NJ: Aton Pharma, Inc; 2007.
2. Katz JI, Kaufman HE, Breslin C, Katz IM. Slow-release artificial tears and the treatment of keratitis sicca. Ophthalmology. 1978;85(8):787-793. 3. Hill JC. Slow-release artificial tear inserts in the treatment of dry eyes in patients with rheumatoid arthritis. Br J Ophthalmol. 1989;73(2):151-154.
4. Lacrisert Clinical White Paper. Available at:
http://www.lacrisert.com/attachments/LacrisertClinicalWhitePaper.pdf. Accessed January 5, 2009.
5.
Werblin TP, Rheinstrom SD, Kaufman HE. The use of slow-release artificial tears in the long-term management of keratitis sicca. Ophthalmology. 1981;88(1):78-81.

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©2012 Valeant Ophthalmics, a division of Valeant Pharmaceuticals North America LLC          Bridgewater, NJ 08807